NAD+
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For research use only. Not for human or animal consumption.
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Properties
Name: |
NAD+ |
Purity: |
~99% as determined by HPLC |
Appearance: |
Supplied as white lyophilized (freeze-dried) powder |
CAS Number: |
53-84-9
|
Also Known As: |
Nicotinamide Adenine Dinucleotide |
Molecular Weight: |
663.43 g/mol |
Molecular Formula: |
C21H27N7O14P2 |
PubChem CID: |
925 |
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Product Name: NAD+ (Nicotinamide Adenine Dinucleotide)
Desription
Nicotinamide Adenine Dinucleotide (NAD+) is a crucial coenzyme found in all living cells. It plays a vital role in numerous fundamental biological processes, including energy metabolism, DNA repair, and cell signaling. NAD+ exists in two forms: an oxidized form (NAD+) and a reduced form (NADH). These two forms are interconverted during metabolic reactions, facilitating the transfer of electrons.
Intended Use:
- This product, Nicotinamide Adenine Dinucleotide (NAD+), is sold exclusively for in vitro laboratory research and development purposes ONLY.
- It is NOT intended for human or veterinary use, consumption, diagnostics, therapeutic applications, or any other use outside of controlled laboratory research environments.
- NAD+ is a fundamental molecule that has been the subject of extensive scientific investigation for decades, contributing significantly to our understanding of cellular biochemistry and metabolism. This product is intended for researchers seeking to further explore the roles and functions of NAD+ in various biological systems and experimental models.
- This product is NOT an FDA-approved drug, dietary supplement, or cosmetic.
Historical Research and References (for informational context only):
The significance of NAD+ has been recognized for over a century. Early research laid the groundwork for understanding its fundamental role in cellular respiration:
-
The significance of NAD+ has been recognized for over a century. Early research laid the groundwork for understanding its fundamental role in cellular respiration. The following references are provided for historical and informational context regarding the scientific discovery and study of NAD+ itself:
- Harden, A., & Young, W. J. (1906). The alcoholic ferment of yeast-juice. Part II. The coferment of yeast-juice. Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character, 77(520), 405–420. URL:
https://doi.org/10.1098/rspb.1906.0020
- Warburg, O., & Christian, W. (1936). Pyridin, the hydrogen-transferring component of fermentation enzymes (Pyridine nucleotide). Biochemische Zeitschrift, 287, 291–328.
- Warburg, O. (1949). Heavy metal prosthetic groups and enzyme action. (P. G. H. Gell, Trans.). Oxford University Press.
- Chambon, P., Weill, J. D., & Mandel, P. (1963). Nicotinamide mononucleotide activation of a new DNA-dependent polyadenylic acid synthesizing nuclear enzyme. Biochemical and Biophysical Research Communications, 11(1), 39-43. URL:
https://doi.org/10.1016/0006-291X(63)90024-X
- Imai, S. I., Armstrong, C. M., Kaeberlein, M., & Guarente, L. (2000). Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature, 403(6771), 795–800. URL:
https://doi.org/10.1038/35002622
- Harden, A., & Young, W. J. (1906). The alcoholic ferment of yeast-juice. Part II. The coferment of yeast-juice. Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character, 77(520), 405–420. URL:
Handling and Storage:
- Storage: Store lyophilized product at to . Protect from moisture and light. Store reconstituted product at to (standard refrigerator temperature).
- Reconstitution: Reconstitute with appropriate sterile laboratory solvents (e.g., sterile water, bacteriostatic water) immediately prior to research use, following established laboratory protocols for peptide handling.Â
- Safety: Handle using appropriate personal protective equipment (PPE) such as gloves, lab coat, and eye protection, within a controlled laboratory environment.Â
Quality Assurance:
- Our NAD+ is rigorously tested for purity and identity using analytical methods such as HPLC. Purity and content is verified for every batch via third party testing.
Further Information and Verification:
-
PubChem (National Institutes of Health, .gov): For comprehensive chemical information on Nicotinamide Adenine Dinucleotide (NAD+), including properties, structures, and links to biomedical literature, search its CAS number (53-84-9) or name on the PubChem website. A direct link to the primary entry is:
https://pubchem.ncbi.nlm.nih.gov/compound/Nicotinamide-Adenine-Dinucleotide
. -
KEGG (Kyoto Encyclopedia of Genes and Genomes - genome.jp/.org): For information on NAD+ as a compound in metabolic pathways:
https://www.genome.jp/dbget-bin/www_bget?C00003
-
ChEBI (Chemical Entities of Biological Interest - ebi.ac.uk - part of EMBL, an intergovernmental organization): For curated information on NAD+:
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:15846
Disclaimer: Purchase of this product signifies an agreement that it will be used solely for legitimate laboratory research purposes by qualified individuals trained in laboratory procedures and safety. The buyer assumes all responsibility for the proper handling, storage, use, and disposal of this product. The seller makes no claims regarding the suitability of this product for any particular research application beyond its specified chemical identity and purity. This product has not been evaluated by the Food and Drug Administration and is not intended to diagnose, treat, cure, or prevent any disease or condition. Historical information is educational and does not imply specific uses of this product. All product descriptions and details found on this website are intended for educational, research and informational purposes only.
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