Clear glass laboratory vial of aqueous solution with a glass pipette and droplet and a storage box in soft focus, representing in vitro stock solution preparation and storage.
Mindful Research

5-Amino-1MQ Solubility and Storage in Aqueous Stock

Updated By: Mindful Research Team2 min read

Key takeaways

  • 5-Amino-1MQ is a water-soluble iodide salt reconstituted in aqueous buffer.
  • Stock math uses the salt MW (286.11 g/mol) actually weighed; convert to the cation (159.21 g/mol) if a method specifies it.
  • 10 mg salt in 1 mL buffer = 10 mg/mL, about 35 mM on the salt basis.
  • Store the solid cold, dry, and dark; aliquot aqueous stocks to limit freeze-thaw.
  • For in vitro research use only.

5-Amino-1MQ is a small-molecule iodide salt that dissolves in aqueous buffer, and its stock-concentration math uses the salt molecular weight weighed out, not the cation mass.

Because it is a cationic salt rather than a lyophilized peptide, handling differs from the store’s peptide guides. This note covers solubility, stock preparation, and storage of the solid and its solutions.

How does it dissolve?

As a small quaternary-type cation supplied as the iodide salt, 5-Amino-1MQ is water-soluble and is generally reconstituted in aqueous buffer. It does not need the acidic solvent that some basic peptides require; background on why solubility varies is in why some peptides won’t dissolve. General reconstitution technique is in how to reconstitute research materials.

How is stock concentration calculated?

Use the mass of solid actually weighed, which is the iodide salt at 286.11 g/mol. For example, dissolving 10 mg of the salt in 1 mL of buffer gives a 10 mg/mL solution; dividing by 286.11 g/mol gives roughly 35 mM expressed on the salt basis. If a method specifies the cation, convert using the cation weight of 159.21 g/mol. Worked unit conversions are in the mg/mL and molarity calculator and the units primer. Concentrations are always expressed in mg/mL or molarity.

How is it stored?

The solid powder is kept cold, dry, and protected from light; prepared aqueous stocks are aliquoted to limit freeze-thaw cycles. The compound chemistry sits in the 5-Amino-1MQ research profile, the material is the 5-Amino-1MQ listing, and reconstitution solution is a common complementary reagent for preparing aqueous stocks.

Related research guides

Research-use note

All materials discussed are supplied for in vitro laboratory research use only, and are not for human or animal use.

Frequently asked questions

Is 5-Amino-1MQ water-soluble?

Yes. As a small iodide salt it is water-soluble and is generally reconstituted in aqueous buffer, without the acidic solvent some basic peptides need. 5-Amino-1MQ

Which molecular weight is used for stock math?

The iodide salt weight, 286.11 g/mol, because that is the solid weighed; convert to the cation (159.21 g/mol) only if a method specifies the cation. mg/mL and molarity

What molarity is 10 mg/mL?

About 35 mM expressed on the iodide-salt basis (10 mg/mL divided by 286.11 g/mol).

How should it be stored?

Keep the solid cold, dry, and protected from light, and aliquot aqueous stocks to limit freeze-thaw cycles. reconstitution guide