Semax is a synthetic heptapeptide, CAS 80714-61-0, sequence Met-Glu-His-Phe-Pro-Gly-Pro (MEHFPGP), molecular formula C37H51N9O10S, molecular weight ~813.9 g/mol — structurally the ACTH(4-7) fragment extended with a C-terminal Pro-Gly-Pro tail.
What is semax?
Semax is a short synthetic peptide used as an in vitro research material. In search and catalogs it appears as semax and peptides semax. It is described here purely by its sequence, structure and identifiers — as a defined laboratory compound. The existing short-peptide research-targets profile covers its receptor-assay context; this page is the structure-and-naming reference.
What is the structure of semax?
Semax joins a four-residue fragment of adrenocorticotropic hormone (ACTH 4-7: Met-Glu-His-Phe) to a three-residue Pro-Gly-Pro tail at the carboxyl terminus. That Pro-Gly-Pro extension is a stabilising motif that slows aminopeptidase cleavage of the parent fragment in solution. Verified identifiers:
| Identifier | Value |
|---|---|
| Sequence | Met-Glu-His-Phe-Pro-Gly-Pro (MEHFPGP) |
| Structural class | ACTH(4-7) fragment + Pro-Gly-Pro tail |
| CAS number | 80714-61-0 |
| PubChem CID | 9811102 |
| Molecular formula | C37H51N9O10S |
| Molecular weight | ~813.9 g/mol |
| UNII | I5FAL2585H |
Why does “peptides semax” return so many different pages?
Because the name is used loosely across the research-supply space, listings vary between the bare heptapeptide and modified forms. The most common modified research form is N-acetyl semax amidate, which has its own identifiers and is covered in the N-acetyl semax amidate chemistry page. Confirming the CAS number and formula is the reliable way to tell which form a listing describes.
How is semax related to Selank?
Semax and Selank are both short synthetic peptides studied as in vitro research materials, but they are structurally unrelated: Selank is a tuftsin-derived heptapeptide with a different sequence. They are grouped only by format, not by structure. Research-grade material is listed on the Semax product page.
Related research guides
- N-Acetyl Semax Amidate: Modified-Form Chemistry and Identity
- Sourcing Semax Research Material: COA and Identity
- Semax: A Short Peptide and Its In-Vitro Research Targets
Research-use note
All materials discussed are supplied for in vitro laboratory research use only, and are not for human or animal use.
