Abstract mitochondrion cross-section with a peptide at the inner membrane representing SS-31.

Sourcing SS-31 as a Research Material: COA & Purity

Key takeaways

When sourcing SS-31, check for a batch-specific COA, HPLC purity, and MS identity.
It is studied in vitro as a mitochondria-targeting peptide that associates with cardiolipin.
A batch COA is tied to your exact lot with dated data.
Supplied as a research material with batch documentation.
For in vitro research use only.

When sourcing SS-31 as a research material, what matters is a batch-specific Certificate of Analysis, HPLC purity, and mass-spectrometry identity confirmation. SS-31 is a mitochondria-targeting research peptide studied in vitro. This guide covers what to check.

Batch-specific COA

A strong COA is tied to the exact lot you receive, with dated analytical data reporting identity, purity, and methods — not a generic spec sheet.

Purity by HPLC

HPLC separates the sample and reports the percentage that is the target compound; a clean dominant peak indicates high purity.

Identity by mass spectrometry

Mass spectrometry confirms the measured molecular weight matches the expected value, confirming identity.

Where to buy SS-31 peptide for research: what a listing should show

Any SS-31 peptide for sale as a research material should be listed by its sequence (D-Arg-Dmt-Lys-Phe-NH₂), CAS number 736992-21-5 and molecular weight 639.8 g/mol, with a batch COA attached. Listings written as "SS31", "SS-31" or "elamipretide" all describe the same compound; the name variants are explained in SS31 peptides, SS-31 and elamipretide: one compound, several names. A listing with no sequence, no CAS number and no batch document is not a research-grade listing.

Happy Peptides supplies SS-31 as a research material with batch documentation. If you are also evaluating the mitochondrial-derived peptide, the same checks are applied in sourcing MOTS-c as a research material.

Find a COA: every SS-31 batch report is listed in our certificate of analysis library, searchable by batch number.

Related research guides

Research-use note

All materials discussed are supplied for in vitro laboratory research use only, and are not for human or animal use.

Frequently asked questions

What should I check when sourcing SS-31?

A batch-specific COA, HPLC purity, and mass-spectrometry identity confirmation. View SS-31

Where can I buy SS-31 peptide for research?

From a supplier that lists the sequence, CAS 736992-21-5 and molecular weight, and attaches a batch COA; Happy Peptides supplies SS-31 with batch documentation for in vitro use. View SS-31

Are SS31 and elamipretide the same as SS-31?

Yes, all three names describe the same aromatic-cationic tetrapeptide; the naming is explained in the identity guide. SS-31 naming guide

How is identity confirmed?

Mass spectrometry matches measured to expected molecular weight, about 640.4 for [M+H]+.

Research use only?

Yes, in vitro laboratory research use only.